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These sheets are frequently utilised as a way to smuggle medications into controlled environments, like prisons, as they might be disguised as ordinary paper and so are difficult to detect by authorities.
, 2012), no reports so far have examined the pharmacological properties of these K2 synthetic cannabinoids or their metabolites at CB2Rs. Therefore, the goal of this analyze was to determine the affinity and intrinsic exercise of JWH-018, JWH-073 and a number of other of their major period I hydroxylated metabolites at human CB2Rs.
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While structurally distinct from Δ9-THC, the synthetic compounds located in K2 items are derivatives in the perfectly characterised aminoalkylindole (AAI) chemical course of ligands that also bind and activate CB1Rs (Manera et al.
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